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Other angles are possible, and will vary depending on the physical properties of the materials involved, including the material of the waveguide, the tissue involved skin, oral tissue, and other tissues , and the material between the waveguide and the tissue air, water, blood, etc. For example, the contact sensor can detect that the detected radiation level is above or below a threshold. Depending on the application, various wavelengths can be used. Apparatus and method for the processing of solid materials, including hard tissues. As such, the waveguide can allow repeatable optical coupling between the device and the skin.

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Apparatus and ponext for high energy photodynamic therapy of acne vulgaris and seborrhea. Controlled removal of human stratum corneum by pulsed laser to enhance percutaneous transport. Methods and apparatus for light induced processing of biological tissues and of dental materials.

The waveguide can be formed of a material that is transmissive to the radiation generated by the sources 22 and 24and, in the present embodiment, is fused silica. Even broader or different wavelength ranges can be used for other purposes or to use other types of radiation sources.

The difference in the two signals is due to the total internal reflection of the light due to the difference in the indices of refraction of the waveguide and the air. The specularly reflected radiation does not penetrate the skin and hence it typically does not zkin any information regarding the skin pigment of interest.

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The device 16 also includes a detector 10 that is optically coupled to waveguide 19 via a filter 8 and polarizer 7. Apparatus for generating a focusable and scannable ultrasonic beam for non-destructive examination. The device can further include a opnwxt for coupling the backscattered radiation exiting from the proximal end to the detector, such as a beamsplitter. Irradiation device, particularly for carrying out photodynamic diagnosis or therapy.

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Medical device applying localized high intensity light and heat, particularly for destruction of the endometrium. A dermatological device for determining a physical characteristic of a portion of skin, comprising a radiation source assembly configured opnedt generate radiation having at least a first wavelength. Laser treatment of cancerization of the oral cavity and apparatus for use therewith.

The device of claim 1wherein said radiation source assembly includes at least one of a light emitting diode LEDa bi-color LED, a tunable radiation source, and a laser radiation source.

Photodynamic cellular and acellular organism eradication utilizing a photosensitive material and surfactant. The removal of the cladding allows a portion of the backscattered opnezt to leak from the core into the sensor's detector.

The device 65 can further include an optical sensor 76such as those discussed above, that is optically coupled to a sidewall of the waveguide 71 for determining contact between the waveguide and the skin.

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In the case where the waveguide 5 is in contact with the tissue 6as shown in FIG. When the device is touching the tissue, substantially more light reenters the waveguide 5 and passes through surface 5 C.

This filter passes the desired wavelengths emitted by sources 2 A and 2 B, but filters out other ponext of radiation noise e.

Apparatus and method of photodynamic eradication of organisms utilizing pyrrolnitrin. Though many materials are possible, the prism in this embodiment is made of CaF 2. Again, the wavelengths and are thought to be preferable, but many other combinations of wavelengths are possible. The use of LEDs in this exemplary embodiment provides a number of advantages. Compositions and methods for treating or preventing skin inflammation via restoration of skin barrier function.

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Opnex and apparatus for temperature control of biologic tissue with simultaneous irradiation. The device of claim 1 wherein said waveguide is configured to totally internally reflect said backscattered radiation along the sidewall when said surface of said waveguide is in contact with said tissue. Detector 73 generates output signals that can be analyzed by a processor 75e. Such detection of the iris can be useful, for example, in devices that must avoid damaging an eye when providing laser or other radiation treatment to the skin.

A processor in communication with the detector processes the signals and calculates a physical characteristic of the tissue region. The treatment radiation can be coupled via one or more optics not shown through a radiation transmissive window 60 such as a sapphire window to the skin.

Its blockage from the detector 10 increases the accuracy of the measurement. The device of claim 1wherein said radiation source assembly is configured to generate radiation having a second wavelength. The device further includes a detector coupled to the waveguide and configured to detect radiation from the source, where the detector generates signals indicative of the level of radiation detected.